Detaillierte Hinweise zur Methadontabletten zur Schmerzbehandlung
Detaillierte Hinweise zur Methadontabletten zur Schmerzbehandlung
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Methadone contains methadone, a mu-agonist opioid with an abuse liability similar to other opioid agonists and is a Schedule II controlled substance. Methadone and other opioids used in analgesia have the potential for being abused and are subject to criminal diversion.
Regardless of the dose determination strategy employed, methadone is most safely initiated and titrated using small initial doses and gradual dose adjustments.
When methadone is used with certain drugs, it may not work as well to treat your condition. This is because the amount of methadone hinein your body may Beryllium decreased. Examples of these drugs include:
Geriatric – The pharmacokinetics of methadone have not been evaluated rein the geriatric population.
After stopping treatment with methadone hydrochloride tablets, flush the unused tablets down the toilet.
Patients should Beryllium apprised of the high risk of relapse to illicit drug use associated with discontinuation of methadone maintenance treatment.
If you have a paralytic ileus (lack of muscle tone hinein the intestines that can cause Us-soldat obstructions), you shouldn’t take this drug.
Pediatric – The pharmacokinetics of methadone have not been evaluated in the pediatric Tierbestand.
Abrupt opioid discontinuation can lead to development of opioid withdrawal symptoms (see PRECAUTIONS). Presentation of these symptoms have been associated with an increased risk of susceptible patients to relapse to illicit drug use and should be considered when assessing the risks and benefit of methadone use.
Patients hinein maintenance treatment should Beryllium titrated to a dose at which opioid symptoms are prevented for 24 hours, drug hunger or craving is reduced, the euphoric effects of self-administered opioids are blocked or attenuated, and the patient is tolerant to the sedative effects of methadone. Most commonly, clinical stability is achieved at doses between 80 to 120 mg/day.
A retrospective series of 101 pregnant, opiate-dependent women who underwent inpatient opiate detoxification with methadone did Methadontabletten 10 mg online not demonstrate any increased risk of miscarriage in the 2nd trimester or premature delivery in the 3rd trimester.
Under the requirements of this REMS program, the drug manufacturer must develop educational programs regarding the safe and effective use of opioids for your doctor.
You and your doctor should monitor certain health issues. This can help make sure you stay safe while you take this drug. These issues include:
Narcotics with mixed agonist-antagonist properties should not Beryllium used for pain control during labor hinein patients chronically treated with methadone as they may precipitate acute withdrawal.